WASHINGTON (AP) ? Democrats and tea party Republicans have killed a GOP plan to give the president more flexibility to apply automatic government spending cuts due to start on Friday.
The failed bill would have required President Barack Obama to try to replace the budget cuts in hopes of shifting money to ease shortfalls in top-priority programs like air traffic control, federal courts and meat inspection.
Democrats and the White House opposed the measure, which would have locked in $85 billion in across-the-board spending cuts through the Sept. 30 end of the budget year. They said the added flexibility would be of limited help.
Pennsylvania Republican Pat Toomey was a sponsor of the measure. He says the measure would allow Obama, quote, to "distinguish between more sensible government spending and less sensible spending."
>>>back now at 8:15 with a florida teen's instructional video that went very, very wrong.
>>hi, guys, it's
tori
. i'm basically going to curl my hair. i think this makes the curls look bigger when you wrap it up. oh, my god. you're kidding me. my hair just burnt off.
>>that expression, priceless. this was posted on youtube just over a week ago. already it has more than 14 million hits and,
tori
locklear is the middle schooler in that video. she's with us, along with celebrity hairstylist ted gibb gibson. good morning to you.
>>good morning.
>>tori
, that had disaster written all over it. you did that in october. the section here is still growing back, wow!
>>yeah.
>>that had to be painful for you when you saw that piece of hair on the
curling iron
.
>>it was.
>>tell me what you thought when you saw that, your reaction.
>>when i saw that, i was in shock. it didn't seem real at first. then i realized, it actually came off.
>>did you smell any burning or get any sense that something was going on?
>>no.
>>you posted that in october, as i mentioned. already 14 million hits. you posted it, rather, last week. this happened in october. why did you wait so long to post it?
>>all right. i had bad grades at the time. i got my laptop taken away. when i got it back, i was going through my pictures and videos and i saw that and was laughing hysterically. i posted it online and also on facebook. and i wasn't supposed to have one.
>>facebook?
>>yeah. it went around and i got grounded.
>>you're grounded now but you're here in new york. ted gibson is helping you out this morning. this is something you've seen professionally.
>>absolutely.
>>what happened?
>>the girls don't necessarily know that the hair has to be 100% dry. use a hairspray in it, just a light control hairspray, spray it on then use an iron. what's great about irons, sometimes they have a dial on them. make sure that you always, always check the dial.
>>did you check the dial?
>>if it's too hot --
>>there wasn't.
>>there wasn't a dial? just hot and on.
>>she confessed to me that she had a leave-in conditioner. it's going to be too heavy, it's going to be wet. it's not going to be dry. the hair has to be 100% dry before you put any
flat iron
or
curling iron
in the hair always.
>>let's see how to do it the right way.
>>you want to take a one-inch section.
>>in her instructional video she said to hold it there for 20 seco seconds or longer.
>>way too long! that is way too long. five to seven seconds is enough. all you want to do is give it some texture, give it some wave. take the iron. you wrap the hair around the iron. you leave the ends out for three to five seconds. that's all you need and all you'll get is a little bit of wave, little bit of texture. what makes it modern is that the ends are a little straighter than they are a full curl on the end.
>>people who use these appliances every day, is that generally not advisable?
>>that is not advisable. you should take a break from the he heat. it's like
heat therapy
. you want to take a break from the heat and not necessarily always use an iron on it every single day.
>>tori
, is there some good that's come out of all of this? you were on "ellen" yesterday, on the "today" show today. so what have you learned about all of this?
>>it's good because i got to experience all this.
>>exactly. and you got to hang out here with
kathie lee
, by the way. sorry for busting in on your turf, lady.
>>no problem.
>>she's not getting her attention here. don't worry. we'll give it to her.
tori
, thank you so much.
tori
locklear.
The costs of wasted food go far beyond the money you may have wasted buying something and letting it spoil. We've talked about ways to stop wasting food before, but if all you really need to know is "How long will this stay fresh and how should I store it," this helpful chart will help.
This chart, sent over to us by our friends at Visual.ly, does a great job at listing some common foods and how long they'll stay fresh and safe to eat based on different storage methods (along with a few that you might be tempted to freeze but really shouldn't.) At the bottom the chart goes into detail about the differences between the "sell by," "use by," and "expires on" dates you commonly see on packaging at the store. Put simply, those dates refer to the quality of the food and how often a store should rotate its stock to ensure freshness?it has nothing to do with the safety of the food.
Its also worth noting that while the chart has good data, don't forget to trust your nose?if you've stored your food properly, you can usually beat most expiration dates and keep your food fresher, longer. For another reference, check out previously mentioned Still Tasty and type in the type of food you're curious about. Otherwise, click the chart below to enlarge, or hit the link below to see it at Visual.ly.
A new landmark study by the?World Health Organization says a host of common, everyday household chemicals pose severe health problems including cancer, asthma, reduced fertility and even birth defects.
According to the study, WHO identified a number of ?synthetic chemicals? which the UN agency said had ?serious implications? for health, even going so far as to suggest that so-called ?gender-bending? compounds found in PVC flooring, kids? toys and even credit cards should be banned in order to protect future generations, recent reports detailing the findings said.
The study said more research was likely needed to flesh out the links between endocrine disrupting chemicals (EDCs), which are found in a number of household chemicals, and ?specific diseases and disorders.?
?Reasonable to suspect? chemical substances are causing harm
WHO researchers said they have discovered links between EDCs and health issues including breast, prostate and thyroid cancers, testicular problems, developmental effects on children?s nervous systems, and attention deficit disorder and hyperactivity in kids.
Scientists at the UN agency also said it is ?reasonable to suspect? chemical substances called phthalates of disrupting female fertility, and also linked the substances to rising rates of childhood diseases such as leukemia.
Researchers labeled the study the most ?comprehensive? report on EDCs so far because it examined and evaluated several chemicals and related evidence rather than just focusing on a single element or compound. The?study is titled, ?State of the Science of Endocrine Disrupting Chemicals.?
A d v e r t i s e m e n t
The findings also raised concerns over bispehnol A, a man-made compound found in many daily items such as tin cans and sunglasses. The substance is believed to interfere with the natural hormones that influence human development and growth.
WHO scientists also said there was ?very strong evidence? in animals that the substances can interfere with thyroid hormones; that could lead to brain damage, loss of intelligence, autism and attention deficit hyperactivity disorder.
Regarding the incidence of prostate?cancer, ?significant evidence? exists that suggests a link with agricultural pesticides, according to a team of international medical experts which examined the data. The UN agency also said wildlife was at risk.
?The diverse systems affected by endocrine-disrupting?chemicals likely include all hormonal systems and range from those controlling development and function of reproductive organs to the tissues and organs regulating metabolism and satiety,? the report said. ?Effects on these systems can lead to obesity, infertility or reduced fertility, learning and memory difficulties, adult-onset diabetes or cardiovascular disease, as well as a variety of other diseases.?
The same report, published 10 years ago, found only ?weak evidence? that said chemicals could affect human?health.
?The latest science shows that communities across the globe are being exposed to EDCs, and their associated risks,? said Dr. Maria Neira, WHO?s Director for Public Health and Environment. She said the agency ?will work with partners to establish research priorities to investigate links to EDCs and human health impacts in order to mitigate the risks,? adding: ?We all have a responsibility to protect future generations.?
?We urgently need more research?
The study backed similar warnings by the?European Environment Agency that were issued last year, warning items like cosmetics and medicines containing EDCs could be harmful to human health.
Earlier,?Natural News reported that EDCs identified in this study may have on the body?s hormone system may have ?significant health implications? for humans. (http://www.naturalnews.com)
According to a UN press release, the report ?calls for more research to understand fully the associations between endocrine disrupting chemicals (EDCs) ? found in many household and industrial products ? and specific diseases and disorders.?
?We urgently need more research to obtain a fuller picture of the health and environment impacts of endocrine disruptors,? Neira said.
New York City-based Enigma is trying to help users make sense of it all. And it?s raised $1.1 million in seed funding to get it started. The company, which is still in beta, looks at publicly available and proprietary data sets across multiple providers, including government, real estate, and finance records.
Get your site exposed. Are you ruining your own campaign?
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In: Aparitii editoriale | | Link ????? 25 vizualizari
WASHINGTON (AP) ? President Barack Obama and his officials are doing their best to drum up public concern over the shock wave of spending cuts that could strike the government in just days. So it's a good time to be alert for sky-is-falling hype.
Over the last week or so, administration officials have come forward with a grim compendium of jobs to be lost, services to be denied or delayed, military defenses to be let down and important operations to be disrupted. Obama's new chief of staff, Denis McDonough, spoke of a "devastating list of horribles."
For most Americans, though, it's far from certain they will have a terrible, horrible, no good, very bad day if the budget-shredder known as the sequester comes to pass. Maybe they will, if the impasse drags on for months.
For now, there's a whiff of the familiar in all the foreboding, harking back to the mid-1990s partial government shutdown, when officials said old people would go hungry, illegal immigrants would have the run of the of the land and veterans would go without drugs. It didn't happen.
For this episode, provisions are in place to preserve the most crucial services ? and benefit checks. Furloughs of federal workers are at least a month away, breathing room for a political settlement if the will to achieve one is found. Many government contractors would continue to be paid with money previously approved.
Warnings of thousands of teacher layoffs, for example, are made with the presumption that local communities would not step in with their own dollars ? perhaps from higher taxes ? to keep teachers in the classrooms if federal money is not soon restored. Education Secretary Arne Duncan says teacher layoffs have already begun, but he has not backed up that claim and school administrators say no pink slips are expected before May, for the next school year.
To be sure, the cuts are big and will have consequences. Knowing what they will be, though, is far from a precise exercise.
And there is a lot of improbable precision in administration statements about what could happen: more than 373,000 seriously ill people losing mental health services, 600,000 low-income pregnant women and new mothers losing food aid and nutrition education, 1,200 fewer inspections of dangerous work sites, 125,000 poor households going without vouchers, and much more.
"These numbers are just numbers thrown out into the thin air with no anchor, and I think they don't provoke the outrage or concern that the Obama administration seeks," said Paul Light, a New York University professor who specializes in the federal bureaucracy and budget. For all the dire warnings, he said, "It's not clear who gets hurt by this."
The estimates in many cases come from a simple calculation: Divide the proscribed spending cut by a program's per-person spending to see how many beneficiaries may lose services or benefits under the sequester.
But in practice, through all the layers of bureaucracy and the everyday smoke and mirrors of the federal budget, there is rarely a direct and measurable correlation between a federal dollar and its effect on the ground.
That has meant a lot of tenuous "could happen" warnings by the administration, not so much "will happen" evidence.
So it was in Health and Human Services Secretary Kathleen Sebelius' letter to Congress laying out likely consequences of the spending cuts for her agency's operations. She said the sequester "could" compromise the well-being of more than 373,000 people who "potentially" would not get needed mental health services, which in turn "could result" in more hospitalizations and homelessness.
Duncan left himself less wiggle room. "This stuff is real," he said last week. "Schools are already starting to give teachers notices."
Asked to provide backup for Duncan's assertion, spokesman Daren Briscoe said it was based on "an unspecified call he was on with unnamed persons," and the secretary might not be comfortable sharing details.
Briscoe referred queries about layoffs to the American Association of School Administrators. Noelle M. Ellerson, an assistant director of the organization, said Monday that in her many discussions with superintendents at the group's just-completed annual meeting, she heard of no layoffs of teachers. While everyone is bracing for that possibility down the road, she said, "not a single one I spoke with had already issued pink slips."
Most school district budgets for the next school year won't be completed for two months, she said, meaning any layoff notices would come in early to mid-May. "No one had yet acted."
School districts in areas set aside for tribal lands or military bases count on Washington for a significant share of their budgets, and are to lose $60 million, or 5 percent of their federal payments, when the sequester starts. Nearly all money to run most of the nation's public schools comes from local sources such as property taxes that are not affected by the federal cuts.
As for the assertion that 600,000 women could be dropped from the Women, Infants and Children Program, that's not to say the rolls would be cut by that number. The actual number is likely to include women who are not enrolled in the program now and could be denied when seeking to join it. Federal officials say the true number will depend on how states can manage their caseloads.
Transportation Secretary Ray LaHood has warned of impending furloughs of air traffic controllers, who may need to take one day off every two weeks, and said air-travel delays are likely across the country. Asked Friday why the airline lobby predicted no major impact on air travel from the sequester, he said, "I don't think they have the information we're presenting to them today."
"The idea that we're just doing this to create some kind of a horrific scare tactic is nonsense," LaHood said. But it's a pressure tactic nonetheless: "What I'm trying to do is to wake up members of the Congress on the Republican side to the idea that they need to come to the table."
However the cuts fall, Light at NYU says the Washington Monument ploy, also known as the Firemen First principle, is at work.
It goes like this: Put someone's budget at risk and the first thing you'll hear is a threat to close a cherished national symbol or lay off firefighters and police, when in fact there are other ways to cut spending.
It so happens the Washington Monument is already closed, for earthquake repair. But Obama indulged in the Firemen First principle quite literally.
He appeared at the White House in front of officers in blue uniforms to warn of the consequences of the sequester. "Emergency responders like the ones who are here today ? their ability to help communities respond to and recover from disasters will be degraded."
The law gives little flexibility to agencies to protect favored programs, except for big ones specifically exempted from the automatic cuts, such as Social Security, Medicare, Medicaid and veterans benefits. FBI and Border Patrol furloughs are expected. Still, the White House has directed agencies to avoid cuts presenting "risks to life, safety or health" and to minimize harm to crucial services.
In the partial government shutdown during his presidency, Bill Clinton and his officials told some tall tales and sketched dark scenarios that didn't come to pass, though some might have if the crisis had lasted weeks or months longer. The shutdown played out over two installments totaling 26 days from mid-November 1995 to early January 1996.
National park properties closed (yes, even the Washington Monument), passport and federal mortgage insurance processing were disrupted and toxic waste cleanup stalled as hundreds of thousands of federal workers went idle, paid retroactively later. But states, communities and private groups stepped up to tide over the neediest, keeping Meals on Wheels rolling with their own resources, for example, until Clinton found emergency money to cover the costs. Warnings that Medicare treatment would be withheld proved unfounded, and veterans got their care.
Contractors, who perform many key services for government, kept working for IOUs. A claim by the government that deportations "have virtually ended" was not so.
The Justice Department told the story of a Florida gas station rejecting the government-issued credit card of a drug-enforcement agent to illustrate the indignity of it all.
But the reality was humdrum: The card had merely expired.
___
Associated Press writers Ricardo Alonso-Zaldivar, Mary Clare Jalonick, Joan Lowy and Philip Elliott contributed to this report.
EDITOR'S NOTE _ An occasional look behind the rhetoric of political figures
Over a quarter of MetroPCS' customer base is now on LTE (26 percent), and the company made $1.3 billion in revenue for Q4 and $5.1 billion total in 2012 as a result, it said. Though revenue was down for Q4 over last year to $122 million compared to $215 million for Q4 2011, profits were up year-over-year by 10 percent to $824 million, and the company said it made a record $1.5 billion EBITDA (before taxes, etc.) The company attributes that in part to a 2.2 million LTE subscriber bump, an increase of 117 percent over Q3 2012, but indicated that it lost 93 thousand subscribers total over the same period. It added that churn (customers leaving to other carriers) fell to 3.4 percent, its lowest level ever. Meanwhile, the carrier said it's proposed Deutsche Telecom-backed merger with T-Mobile is moving along swimmingly with a definitive proposal filed yesterday. It anticipates "closing the transaction in early April" ahead of schedule, which it says would make MetroPCS "the leading value wireless carrier inthe United States."
An experimental type of tiny lithium-based batteries promised to wirelessly charge wearable gadgets, implantable brain-wave monitors, or other bionic devices.
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An ultra-stretchy battery could one day be used to power bionic eyeballs, brain-wave monitoring devices and robotic skins, new research suggests.
The new device, which embeds tiny lithium-based batteries in a silicone sheet, can stretch up to three times its initial length and could be recharged wirelessly, Yonggang Huang, study co-author and a mechanical engineer at Northwestern University, wrote to LiveScience in an email.
The new battery is described today (Feb. 26) in the journal Nature Communications.
Powering devices
For decades, science-fiction writers have envisioned dystopian worlds in which humans and machines are seamlessly integrated with bionic implants. But powering the?cyborg?future requires a way to conform power sources to these futuristic devices. [9 Cyborg Enhancements Available Right Now]
Other researchers have developed stretchy and?paper-thin batteries?before, but most didn't deform much or have the ability to recharge wirelessly, Huang wrote.
Toward that end, Huang and his colleagues embedded tiny lithium-ion batteries in a framework of conducting wires arranged in a repeating S-shaped pattern that, like a fractal, looks similar at several scales. The whole arrangement is printed onto a stretchable silicone sheet. The wires themselves are brittle, but uncoil like a spring, allowing the whole device to be flexible without forcing the delicate lithium-ion batteries to break.
To demonstrate that the concept actually worked, the team powered a red light-emitting diode (LED) while stretching and twisting the battery.
The researchers envision the battery being used for?wearable gadgets, implantable brain-wave monitors, or other bionic devices.
While the new design is incredibly innovative, it wouldn't produce enough power to keep a laptop, or even a large light bulb, running, said Gao Liu, a chemist at Lawrence Berkeley National Laboratory who is developing stretchable batteries for transportation systems, but who was not involved in the study. That means it mainly would be useful for a few narrow applications, such as biological implants that don't require very much power, Liu said.
"It's for a niche market," Liu told LiveScience. "You really need to find a market where you don't really need much energy, but you need to deliver the energy on the spot, where you couldn't use a wire."
Follow LiveScience on Twitter?@livescience. We're also on?Facebook?&?Google+.?
Copyright 2013?LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Apparently missile launches and stealth fighters aren?t the only things keeping Iranian Photoshoppers busy these days: First lady Michelle Obama?s shoulder-baring Oscars dress got some digital tailoring to meet Tehran?s standards, as well. First lady Michelle Obama, appearing on screen, and actor Jack Nicholson present the award for best picture during??
Obama wore the shiny Naeem Khan number at the White House to announce the Best Picture winner? ?Argo,? the thriller based on a CIA operation to rescue Americans in post-revolution Iran.
It was apparently too much for Iran's semiofficial Fars News Agency, which modified Obama?s gown for its online report.
(Hat tip: Enduring America via Agence France-Presse photographer Patrick Baz)
LAS VEGAS (AP) ? Police are seeking a 26-year-old man as the prime suspect in last week's pre-dawn shooting and crash on the Las Vegas Strip that killed three people and injured several others
The black SUV used as a getaway car was found Saturday as police named Ammar Harris in connection with the shooting and six-vehicle chain-reaction carnage Thursday on the neon-lit boulevard near the Bellagio, Caesars Palace, Bally's and Flamingo resorts,
An aspiring rapper who was driving a Maserati was shot to death, while two people in a taxi died in the crash.
"His location is unknown," police Capt. Chris Jones said of Harris, who sometimes goes by the name Ammar Asim Faruq Harris. Police say he has been arrested for working as a pimp.
Police released a photo that was taken when Harris was arrested last year on pandering, kidnapping, sexual assault and coercion charges. The disposition of that case was not immediately known.
The photo shows Harris with tattoos on his right cheek and words on his neck above an image that appeared to depict an owl with blackened eyes. Jones warned that Harris should be considered armed and dangerous.
Police had been searching for the black Range Rover, with blackout windows and distinctive black rims, since it was last seen speeding from the shooting. It was located at an apartment complex just a couple of blocks east of the neon-lit boulevard, and was impounded as evidence, Jones said.
The shooting killed Kenneth Wayne Cherry Jr., who was driving the dark gray Maserati that was peppered by gunfire from the SUV. Taxi driver Michael Boldon and passenger Sandra Sutton-Wasmund, of Maple Valley, Wash., died when the Maserati hit their taxi, which exploded in flames.
Boldon, 62, was a family man who moved from Michigan to Las Vegas. Sutton-Wasmund, 48, was a businesswoman and mother of three.
A passenger in the Maserati was wounded in the arm and four people from four other vehicles were treated for non-life-threatening injuries. The Maserati passenger was cooperating with investigators. His name hasn't been made public.
The shocking chain of events had family members and friends in Las Vegas, California, Michigan and Washington trying to grasp the blink-of-an-eye finality of it all.
"My son was a good boy," Kenneth Cherry Sr. told reporters Saturday in a news conference convened by Las Vegas lawyers Vicki Greco and Robert Beckett.
Beckett said they wanted to respond to rumors that the 27-year-old son ? who produced a rap video using the name Kenny Clutch ? was a gangster and a troublemaker. The attorneys had represented his son, and now represent his estate and the family.
"My son was a victim just like the two people in that taxi," Kenneth Cherry Sr. said. "Trouble found him. The people in the taxicab, trouble found them."
Court records show Cherry had no criminal cases or convictions in Las Vegas, and police said there was no record of arrests.
The Clark County coroner determined that Kenny Cherry died of at least one gunshot to the chest. Boldon and Sutton-Wasmund died of injuries in the crash. All three deaths were ruled homicides.
Police say the shooting appeared to stem from an argument at the valet area of the upscale Aria resort-casino about a block south of the crash scene. The shooting happened after a night featuring Morocco-born rapper French Montana at Aria nightclub Haze.
Cherry's parents live in Emeryville, Calif., and the father said his son's body would be taken back to Oakland. He said his son started a music career there and was recognized by other rappers within a West Coast hip-hop strain called hyphy.
Cherry wasn't well-known in wider music circles, according to Chuck Creekmur, CEO of AllHipHop.com.
Kenny Clutch's YouTube music video, "Stay Schemin," shows scenes of hotels along the Strip as he sings about paying $120,000 for his Maserati.
"One mistake change lives all in one night," he raps in one verse.
Kenneth Cherry Sr., who said he runs a cellphone business, said he helped his son make payments on the Maserati. He said he last spoke to him on Wednesday, when they talked about the high cost of the son's cellphone use.
Cherry Sr. described his son as an entrepreneur but didn't say how he made money or if he had jobs other than his music production.
Boldon's family in Las Vegas was struggling to cope with his death, said Tehran Boldon, the taxi driver's younger brother.
Boldon's sister, Carolyn Jean Trimble, said Boldon was a father, a grandfather and a car race enthusiast who drove a Mercedes when he wasn't in a cab. He owned a clothing store in Detroit and worked at a car dealership, his sister said, and drove taxis after moving to Las Vegas about 1? years ago.
The irony that a man with a taste for beautiful cars was killed by a sports car wasn't lost on Trimble.
"He would be tickled to death: 'Damn, of all things, a Maserati hit me, took me out like that,'" she said. "I'm happy he didn't suffer."
In Washington, Sutton-Wasmund co-owned a dress shop, said Debbie Tvedt, the office manager for a Maple Valley plumbing company that Sutton-Wasmund started with her husband, James Wasmund. Sutton-Wasmund was in Las Vegas attending a trade show with her business partner.
"It's a big loss," Tvedt said in a telephone interview with AP.
The Maple Valley-Black Diamond Chamber of Commerce website said Sutton-Wasmund was a board member from 2004 to 2011 before becoming a marketing representative.
A phone message left for James Wasmund was not immediately returned.
The famously glowing, always-open Las Vegas Strip was closed for some 15 hours after the crash. Nevada Highway Patrol Sgt. Eric Kemmer recalled a similarly long closure after the 1996 drive-by slaying of rapper Tupac Shakur.
That shooting ? involving assailants opening fire on Shakur's luxury sedan from a vehicle on Flamingo Road ? happened about a block away from Thursday's crash.
The Shakur killing has never been solved.
___
Associated Press writers Michelle Rindels in Las Vegas, Garance Burke in San Francisco, Kathy McCarthy in Seattle and AP Music Writer Mesfin Fekadu in New York contributed to this report.
President Kirchner announced last month the government will invest $1 billion in the country?s railways, but critics say that may be too little too late.
By Jonathan Gilbert,?Correspondent / February 22, 2013
Relatives of the victims of a train crash attend a one-year anniversary ceremony at the Once train station in Buenos Aires, Argentina, Friday.
Victor R. Caivano/AP
Enlarge
Paolo Menghini's t-shirt bears the face of his son, Lucas, a?victim of one of Argentina's deadliest train accidents, which occurred?a year ago today.
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The crash at Once train station in Buenos Aires killed a total of 51 people, and will be commemorated this evening by the victims'?families, led by Mr. Menghini. Argentina?s trains, however, are still?unsafe.
The crash at Once was not an isolated incident. In the first six?months of 2012, there were more than 1,200 accidents and 190 deaths on?Argentina?s main train lines, according to a government document.
The grieving families blame the current government of Cristina Fern?ndez de Kirchner for the deaths of their relatives, saying it did?nothing to improve a system that deteriorated after it was privatized?in the 1990s.
?The government is not a bystander,? says Menghini, whose son was 20?when he died. ?It stands accused. It knew what could happen and did?nothing.? Two former government transport secretaries, Ricardo Jaime and Juan Pablo Schiavi, are indicted in the case, but a trial date has?yet to be set.
Argentina?s railways were privatized at the beginning of the 1990s,?when concessions for various routes were auctioned off by Carlos?Menem?s administration. The contracts, however, favored the operators?and made it difficult to enforce sanctions and fines, says Pablo?Martorelli, president of the Argentine Railway Institute. He believes?a period of increased state control is forthcoming.
?The government allowed the companies to manage themselves. They stopped investing, and complaints about safety and security fell on?deaf ears,? says Sergio Garc?a, editor of Todo Trenes magazine,?dedicated to the railway industry.
President Kirchner announced last month the government will invest $1?billion in the country?s railways, and will replace the aging trains?of the Sarmiento line, along which the crash took place, with 400 new?Chinese wagons. In July, it withdrew the concession held by Trenes de?Buenos Aires (TBA) to operate the Sarmiento and Mitre lines.
But critics say the moves are belated.
?Once is the best example of Kirchnerism?s failure to act,? says?Leandro Bullor, an analyst at the University of Buenos Aires, using?the term that refers to Argentina?s politics since 2003, when N?stor Kirchner, the President's late husband and predecessor, came to power.
Kirchnerism also allowed years of mismanagement of oil company YPF before renationalizing it last year, Mr. Bullor says. In the case of the railways, despite government spending on the network, politicians?are believed to have allowed a handful of businessmen to misappropriate?substantial state subsidies while ignoring damning safety reports.?Alleged corruption has been at the heart of recent protests against?Kirchner.
Since 1991, Argentina?s usable railway network has dropped by 9,300?miles to around 11,800 miles today. Only 3,700 miles are considered safe for?passengers, who are packed into carriages. Inter-city journeys?are slow: It takes 20 hours to travel the nearly 500 miles from C?rdoba to Buenos Aires.
?It?s not enough to buy new trains,? says Mr. Garc?a. ?The tracks are?decrepit. There needs to be a long-term plan.?
The current government has repeatedly failed to mention Once as it seeks to absolve itself of responsibility for the crash, victims' families say. Kirchner only mentioned the crash once over the course of 11 months, in addition to offering her condolences to the victims? families last?night.
Her supporters pin the blame on former President Menem, but he is an?overused scapegoat for Argentina?s current problems, says Bullor, the?analyst.
?Fifty-one people died because of this government?s indolence,? saysPaolo Menghini. ?There needs to be a profound change since, as things stand, the tragedy of Once could repeat itself tomorrow.?
I was barraged by TV commercials about "viscosity and thermal breakdown" throughout my youth, and those relentless ad campaigns enabled me to visualize the tortuous conditions inside a combustion chamber. But there's nothing quite like picking an expert's brain to reinforce how much you don't know about the intricacies of engine lubrication.
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A recent chat with Royal Purple's Kyle Neal uncovered a few of the details behind the black art (pun intended) of oil design. Turns out that 75 to 80 percent of oil is made of a base stock, but it's the additives, which constitute the last 20 percent or so, that differentiate different brands like Castrol, Mobil, and the like. Those chemical x factors can incorporate everything from detergents and corrosion inhibitors to acid neutralizers and adhesion agents which help keep the oil on key engine parts at startup, where 80 percent of wear occurs. While some companies buy their additives from multi-billion dollar companies like Lubrizol, which is owned by investment tycoon Warren Buffett, Royal Purple has manufactured their own additives for 26 years running.
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The Porter, Texas-based company was named after the combination of red and blue die which gave it a "royal" hue, and their proprietary Synerlec is one of the common threads between their range of products, which encompass everything from fuel injection detergents to Max Cleaner, which helps eliminate carbon soot that can develop on motorcycle engine intakes due to the high ethanol content in today's fuel. The science behind these products may not be as catchy as slickly produced TV ads, but it sure is fascinating to gearhead geeks like me.
Contact: Dorsey Griffith dorsey.griffith@ucdmc.ucdavis.edu 916-734-9118 University of California - Davis Health System
(SACRAMENTO, Calif.) A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found.
Paramita GhoshMen with prostate cancer that has spread to other parts of the body, known as metastatic cancer, and who have had their testosterone lowered with drug therapy are most likely to benefit. The study, recently published in Endocrine-Related Cancer, was conducted in prostate cancer cells and in mice.
Lowering of testosterone, also known as androgen-deprivation therapy, has long been the standard of care for patients with metastatic prostate cancer, but life expectancies vary widely for those who undergo this treatment. Testosterone is an androgen, the generic term for any compound that stimulates or controls development and maintenance of male characteristics by binding to androgen receptors.
The current findings hold promise for GCP therapy as a way to extend life expectancy of patients with low response to androgen-deprivation therapy.
Paramita Ghosh, an associate professor in the UC Davis School of Medicine, led the pre-clinical study with a team that included UC Davis Comprehensive Cancer Center Director Ralph de Vere White, a UC Davis distinguished professor of urology. Ruth Vinall in the UC Davis Department of Urology and Clifford Tepper in the UC Davis Department of Biochemistry and Molecular Medicine directed the studies in mice; Ghosh's laboratory conducted the cell studies.
The research focused on GCP, a proprietary extract cultured from soybeans and shiitake mushrooms and marketed by Amino-Up of Sapporo, Japan. Researchers found that the combination of the compounds genistein and daidzein, both present in GCP, helps block a key mechanism used by prostate cancer cells to survive in the face of testosterone deprivation.
The research team had earlier shown that when a patient's androgen level goes down, cancerous prostate cells kick out a protein known as filamin A, which is otherwise attached to the androgen receptor in the cell's nucleus. The androgen receptor regulates growth of prostate cancer cells. Once filamin A leaves the cancerous cell's nucleus, that cell no longer requires androgens to survive. Thus, loss of filamin A allows these cells to survive androgen deprivation, at and the cancer essentially becomes incurable.
The paper, titled "Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization," shows for the first time that GCP keeps filamin A in the nucleus. As long as this protein remains attached to the androgen receptor, the cancerous cells need androgens to survive and grow. They die off when starved of androgens, thus prolonging the effects of androgen deprivation, which ultimately prolongs the patient's life.
The team's hypothesis is that metastatic prostate cancer patients with the weakest response to androgen-deprivation therapy could be given GCP concurrently with androgen deprivation therapy to retain Filamin A in the nucleus, thereby allowing cancer cells to die off.
De Vere White is now pursuing funding to begin GCP human clinical trials. Because GCP is a natural product rather than a drug, and requires fewer government approvals, it's expected that these trials will proceed rapidly once funded.
"We should know within the first eight months or so of human clinical trials if GCP works to reduce PSA levels," says de Vere White, referring to prostate-specific antigen levels, a tumor marker to detect cancer. "We want to see up to 75 percent of metastatic prostate cancer patients lower their PSA levels, and GCP holds promise of accomplishing this goal. If that happens, it would probably be a greater therapy than any drug today."
###
The research was supported by a Biomedical Laboratory Research and Development service Merit Award (I01BX000400) from the Department of Veterans Affairs and by R01CA133209 from the National Cancer Institute.
Other authors were Benjamin A. Mooso, Sheetal Singh, Salma Siddiqui, and Maria Mudryj of the VA Northern California Health Care System; Ruth L. Vinall, Rosalinda M. Savoy, Jean P. Cheung, and Yu Wang of the UC Davis Department of Urology; Clifford G. Tepper, Anthony Martinez, and Hsing-Jien Kung of the UC Davis Department of Biochemistry and Molecular Medicine; and Roble G. Bedolla of the University of Texas Health Science Center at San Antonio.
UC Davis Comprehensive Cancer Center is the only National Cancer Institute-designated center serving the Central Valley and inland Northern California, a region of more than 6 million people. Its specialists provide compassionate, comprehensive care for more than 9,000 adults and children every year, and access to more than 150 clinical trials at any given time. Its innovative research program engages more than 280 scientists at UC Davis, Lawrence Livermore National Laboratory and Jackson Laboratory (JAX West), whose scientific partnerships advance discovery of new tools to diagnose and treat cancer. Through the Cancer Care Network, UC Davis collaborates with a number of hospitals and clinical centers throughout the Central Valley and Northern California regions to offer the latest cancer care. Its community-based outreach and education programs address disparities in cancer outcomes across diverse populations. For more information, visit http://cancer.ucdavis.edu.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Contact: Dorsey Griffith dorsey.griffith@ucdmc.ucdavis.edu 916-734-9118 University of California - Davis Health System
(SACRAMENTO, Calif.) A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found.
Paramita GhoshMen with prostate cancer that has spread to other parts of the body, known as metastatic cancer, and who have had their testosterone lowered with drug therapy are most likely to benefit. The study, recently published in Endocrine-Related Cancer, was conducted in prostate cancer cells and in mice.
Lowering of testosterone, also known as androgen-deprivation therapy, has long been the standard of care for patients with metastatic prostate cancer, but life expectancies vary widely for those who undergo this treatment. Testosterone is an androgen, the generic term for any compound that stimulates or controls development and maintenance of male characteristics by binding to androgen receptors.
The current findings hold promise for GCP therapy as a way to extend life expectancy of patients with low response to androgen-deprivation therapy.
Paramita Ghosh, an associate professor in the UC Davis School of Medicine, led the pre-clinical study with a team that included UC Davis Comprehensive Cancer Center Director Ralph de Vere White, a UC Davis distinguished professor of urology. Ruth Vinall in the UC Davis Department of Urology and Clifford Tepper in the UC Davis Department of Biochemistry and Molecular Medicine directed the studies in mice; Ghosh's laboratory conducted the cell studies.
The research focused on GCP, a proprietary extract cultured from soybeans and shiitake mushrooms and marketed by Amino-Up of Sapporo, Japan. Researchers found that the combination of the compounds genistein and daidzein, both present in GCP, helps block a key mechanism used by prostate cancer cells to survive in the face of testosterone deprivation.
The research team had earlier shown that when a patient's androgen level goes down, cancerous prostate cells kick out a protein known as filamin A, which is otherwise attached to the androgen receptor in the cell's nucleus. The androgen receptor regulates growth of prostate cancer cells. Once filamin A leaves the cancerous cell's nucleus, that cell no longer requires androgens to survive. Thus, loss of filamin A allows these cells to survive androgen deprivation, at and the cancer essentially becomes incurable.
The paper, titled "Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization," shows for the first time that GCP keeps filamin A in the nucleus. As long as this protein remains attached to the androgen receptor, the cancerous cells need androgens to survive and grow. They die off when starved of androgens, thus prolonging the effects of androgen deprivation, which ultimately prolongs the patient's life.
The team's hypothesis is that metastatic prostate cancer patients with the weakest response to androgen-deprivation therapy could be given GCP concurrently with androgen deprivation therapy to retain Filamin A in the nucleus, thereby allowing cancer cells to die off.
De Vere White is now pursuing funding to begin GCP human clinical trials. Because GCP is a natural product rather than a drug, and requires fewer government approvals, it's expected that these trials will proceed rapidly once funded.
"We should know within the first eight months or so of human clinical trials if GCP works to reduce PSA levels," says de Vere White, referring to prostate-specific antigen levels, a tumor marker to detect cancer. "We want to see up to 75 percent of metastatic prostate cancer patients lower their PSA levels, and GCP holds promise of accomplishing this goal. If that happens, it would probably be a greater therapy than any drug today."
###
The research was supported by a Biomedical Laboratory Research and Development service Merit Award (I01BX000400) from the Department of Veterans Affairs and by R01CA133209 from the National Cancer Institute.
Other authors were Benjamin A. Mooso, Sheetal Singh, Salma Siddiqui, and Maria Mudryj of the VA Northern California Health Care System; Ruth L. Vinall, Rosalinda M. Savoy, Jean P. Cheung, and Yu Wang of the UC Davis Department of Urology; Clifford G. Tepper, Anthony Martinez, and Hsing-Jien Kung of the UC Davis Department of Biochemistry and Molecular Medicine; and Roble G. Bedolla of the University of Texas Health Science Center at San Antonio.
UC Davis Comprehensive Cancer Center is the only National Cancer Institute-designated center serving the Central Valley and inland Northern California, a region of more than 6 million people. Its specialists provide compassionate, comprehensive care for more than 9,000 adults and children every year, and access to more than 150 clinical trials at any given time. Its innovative research program engages more than 280 scientists at UC Davis, Lawrence Livermore National Laboratory and Jackson Laboratory (JAX West), whose scientific partnerships advance discovery of new tools to diagnose and treat cancer. Through the Cancer Care Network, UC Davis collaborates with a number of hospitals and clinical centers throughout the Central Valley and Northern California regions to offer the latest cancer care. Its community-based outreach and education programs address disparities in cancer outcomes across diverse populations. For more information, visit http://cancer.ucdavis.edu.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
The costs of wasted food go far beyond the money you may have wasted buying something and letting it spoil. We've talked about ways to stop wasting food before, but if all you really need to know is "How long will this stay fresh and how should I store it," this helpful chart will help. 
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New York City-based Enigma is trying to help users make sense of it all. And it?s raised $1.1 million in seed funding to get it started. The company, which is still in beta, looks at publicly available and proprietary data sets across multiple providers, including government, real estate, and finance records.
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Public release date: 20-Feb-2013
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